Digital Tbucket Tank (DTT)

Killing bacteria with lasers. Light copes with antibiotic-resistant pathogens

The world is facing a growing crisis Antibiotic resistance faced. The excessive use of Antibiotics in medicine, the food industry and in cosmetics leads to the occurrence of antibiotic-resistant bacteria. The penetration of antibiotics into the environment, with concentrations in some rivers exceeding safe levels by 300 times, forces the pathogens to continuously develop antibiotic resistance. Hundreds of bacterial antibiotic resistance genes have even been discovered in the intestines of children. Without new antibiotics or other solutions, the scenario of people dying again from common infections or currently harmless diseases becomes real.

A strategy outside of the chemical repertoire is use physical methods such as ultraviolet light, gamma radiation, or heat. While these methods are effective in inactivating pathogens, they cause severe tissue damage and therefore cannot be used in clinical practice.

It is for this reason that some scientists are interested in this visible light. At low intensity it is gentle on the tissue and at the same time has the ability to inactivate bacteria, viruses and other pathogens. Specialists studying this problem are especially interested in Femtosecond laserthat emit ultrashort light pulses, the duration of which is specified in femtoseconds (1 femtosecond is 1/1 000 000 000 000 000 second).

 Image source: Pixabay / Source

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Spread of brain tumors explained using principles of fluid physics

Josef Käs from the University of Leipzig and Ingolf Sack from the Charité-Universitätsmedizin Berlin have shown that the spread of Brain tumor cells depends on both their physical and biomechanical properties. According to the researchers, a small change in the elasticity of glioma cells - the most dangerous brain tumor - significantly changes its ability to metastasize.

Sack is a chemist and Käs is a physicist. Both specialize in cancer research, but from different perspectives. Sack studies the mechanical properties of fabrics and has the technology of Magnetic resonance elastography developed a combination of low frequency vibrations and Magnetic resonance. It is used to track the progress of diseases. Käs, on the other hand, works with one optical trap, in which soft miniature objects such as cells can be deformed with the help of lasers to create their elasticity and to investigate deformability.

 Image source: Pixabay / Source

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Congratulations to Silent High-Tech Solutions - SOTOS

Digital Think Tank warmly congratulates the StartUp Silent Ht Solutions under the leadership of PD Dr. Martin Friedrich for the third prize in the “Starter Prize 2021”! We wish you continued success with the innovative product. For those who want to see a short sketch of the project, here is a video:.

Enjoy! 

Click here for the video

Electronic plasters for monitoring bones

A team of researchers from the University of Arizona developed a super-thin wireless device that works permanently with the Bone surface merges. A new electronic circuit solution of this kind, the so-called Osseo-Surface electronics, is in an in Nature Communications published article.


The outer layers of the bone are renewed in the same way as the outer layers of the skin. So if a traditional glue was used to attach something to the bone, it would fall off after a few months. That is why the co-author of the study, John Szivek from the BIO5 Institute, developed an adhesive that Calcium molecules contains, the atomic structure of which is similar to that of bone cells. The chip is very thin - as thick as a piece of paper - so it doesn't irritate the muscle tissue that comes into contact with the bones.

 Image source: Shutterstock / Source

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Cells SimCity

This is what a human cell looks like up close. The unusual picture was from the NASA recorded with the help of cryo-electron microscopy. NASA has got us used to breathtaking images from the cosmos. Edited and colored images of distant nebulae and galaxies have always caught the imagination. This time, however, the agency associated with outer space helped create an image of one of the smallest objects that surrounds us - the cells of our body

Image source: Digizyme / NASA / Stanford University

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An unusual feature of the human brain. We have an amazingly low density of ion channels

Scientists at MIT were amazed to find that compared to other mammals, human neurons have a lower density of ion channels than one would expect. Ion channels generate the electrical impulses through which Neurons communicate. This is another amazing observation about the structure of the Brain.

Scientists hypothesize that because of the lower density of ion channels, the human brain has evolved to work more efficiently and save energy for other processes required to perform complex cognitive tasks. If the brain can save energy by reducing the density of ion channels, it can use the saved energy for other processes, said Professor Mark Harnett of the McGovern Institute for Brain Research on MIT.

Image source: Shutterstock;

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External peer review of the RT-PCR test for the detection of SARS-CoV-2 reveals 10 essential scientific shortcomings on a molecular and methodological level: Consequences for false positive results.

Dear reader, today we will start with a quote from Prof. Albert Einstein, (from a radio broadcast for United Jewish Appeal, April 11, 1943):

"The pursuit of truth and knowledge is one of the most beautiful things that a person is capable of, even if pride in this pursuit is mostly on the lips of those who are least filled with such pursuits."

The world has been with the for almost a year Corona pandemic employed. A great many measures have been taken to control the situation. We at the DTT Science-Tank Team have never addressed the subject of the corona pandemic. The reason is quite simple. In order to form a scientific opinion on a topic, you need a healthy and respectful dispute, especially in science. Good scientists have always done that. If you just look at the history of quantum physics and the various legendary feuds between scientists, you learn how science works. Unfortunately took place in the present Corona crisis Hardly tired of a proper dispute, until now.

It goes without saying that the basis for various measures by governments is the PCR tests represent.

The work published in early 2019: Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR - to be found here (https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2020.25.3.2000045)

Authors:

Victor M Corman, Olfert Landt, Marco Kaiser, Richard Molenkamp4, Adam Meijer, Daniel KW Chu6, Tobias Bleicker1, Sebastian Brünink, Julia Schneider, Marie Luisa Schmidt1, Daphne GJC Mulders4, Bart L Haagmans, Bas van der Veer, Sharon van den Brink , Lisa Wijsman, Gabriel Goderski, Jean-Louis Romette, Joanna Ellis, Maria Zambon, Malik Peiris, Herman Goossens, Chantal Reusken, Marion PG Koopmans, Christian Drosten   

is known. It was and is perhaps still considered the main trigger for the implementation of PCR tests.

Without going into the details of the work, we'd like to go into one Review report to draw attention:

Image source: Pixabay

External peer review of the RTPCR test to detect SARS-CoV-2 reveals 10 major scientific flaws at the molecular and methodological level: consequences for false positive results - to be found here (https://cormandrostenreview.com/report/)      

Autoren:

Pieter Borger, Bobby Rajesh Malhotra, Michael Yeadon, Clare Crai, Kevin McKernan, Klaus Steger, Paul McSheehy, Lidiya Angelova, Fabio Franchi, Thomas Binder, Henrik Ullrich, Makoto Ohashi, Stefano Scoglio, Marjolein Doesburg-van Kleffens, Dorothea Gilbert, Rainer Klement, Ruth Schruefer, Berber W Pieksma, Jan Bonte, Bruno H Dalle Carbonare, Kevin P Corbett, Ulrike Kämmerer             

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How will artificial intelligence help prevent premature births?

According to a report by the World Health Organization (WHO), 15 million newborns are affected by spontaneous premature births every year. Up to a million of them die. Many face lifelong disabilities. The commonly used manual analysis of Ultrasound images allows detection of possible problems, but is not a perfect method. This problem is recognized by doctors. In 2017, Nicole Sochacki-Wójcicka (about to specialize in gynecology) and Jakub Wójcicki contacted Dr. Tomasz Trzciński from the Faculty of Electronics and Information Technology at the Warsaw University of Technology (WUT) and asked if it was possible to start a project to predict spontaneously Premature births using neural networks to realize. Then a research team was formed and work began. The first effects are already known. Our solution can support computer diagnostics and provide a more accurate prediction of spontaneous premature births, "explains Szymon Płotka, a graduate of the Warsaw University of Technology and one of the members of the team working on the project.

Image source: Pixabay

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